This disease is well known, and needs no descrip-tion. The best cure for it is the duke of Portland's powder, which is now sold in most apothecaries shops in London. A dram of this is to be taken every morning for three months, in a cup of wine, water, broth, or tea. Then three quarters of a dram for three months longer, and half a dram every morning for fix months more, fasting an hour and a half after each dose. After the first year, it will be sufficient to take half a dram every other day. The patient must not be discouraged if he perceives no great amendment at first. It works slow, but sure, and it may be sometimes two years before he receives any benefit. A dram of flower of brimstone taken every morning in a spoon-ful of milk, has prevented the gout for many years.