But whenever anyone is so imprudent, as to destroy this vicarious local symptom, the organism is ready to cause the internal syphilis to break out into the venereal disease, since the general venereal disease dwells in the body from the first moment of infection.

For in the spot, into which at the impure coition the syphilitic miasma had been first rubbed in and had been caught, it is, in the same moment, no more local; the whole living body has already received (perceived) its presence, the miasma has already become the property of the whole organism. All wiping off and washing off, however speedy, and with whatever fluid this be done (and as we have seen, even with the exsec-tion of the part affected), it is too late - is in vain. There is not to be perceived, indeed, any morbid transmutation in that spot during the first days, but the specific venereal transformation takes place in the internal of the body irresistibly, from the first moment of infection until syphilis has developed itself throughout the whole body, and only then (not before), nature loaded down by the internal malady, brings forth the local symptom peculiar to this malady, the chancre, usually in the place first infected; and this symptom is intended by nature to soothe the internal completed malady.

Therefore, also, the cure of the venereal disease is effected most easily and in the most convincing manner, so long as the chancre (the bubo) has not yet been driven out by local applications, so long as the chancre (the bubo) still remains unchanged, as a vicarious symptom of the internal syphilis. In this state, and especially when it is not yet complicated with Psora, it may be asserted from manifold experience and with good reason, that there is on earth no chronic miasma, no chronic disease springing from a miasma, which is more curable and more easily curable than this.

In this first simple state and simple cure, when the chancre (or the bubo) is still present, and there is no complication with a developed Psora, no prominent chronic ailment from a Psoric origin (usually there is none such with young, lively persons), and with latent Psora syphilis combines as little as sycosis - in this first state it needs only one little dose of the best mercurial remedy, in order to cure thoroughly and forever the whole syphilis with its chancre, within fourteen days. In a few days after taking such a dose of mercury, the chancre (without any external application) becomes a clean sore with a little mild pus, and heals of itself - as a convincing proof, that the venereal malady is also fully extinguished within; and it does not leave behind the least scar, or the least spot, showing any other color than the other healthy skin. But the chancre, which is not treated with external application, would never heal, if the internal syphilis had not been already annihilated and extinguished by the dose of mercury; for so long as it exists in its place, it is the natural and unmistakable proof of even the least remainder of an existing syphilis.

I have, indeed, in the second edition of the first part of Materia Medica Pur a (Dresden, 1822), described the preparation of the pure semi-oxide of mercury, and I still consider this to be one of the most excellent anti-syphilitic medicines; but it is difficult to prepare it in sufficient purity. In order, therefore, to reach this wished for goal in a still simpler manner, free from all detours, and yet just as perfectly (for in the preparation of medicines we cannot proceed in too simple a manner), it is best to proceed in the way given below, so that one grain of quite pure running quick-silver is triturated three times, with 100 grains of sugar of milk each time, up to the millionth attenuation, in three hours, and one grain of this third trituration is dissolved, and then potentized through -twenty-seven diluting phials up to (x) the decillionth degree, as is taught at the end of this volume, with respect to the dynamization of the other dry medicines.

I formerly used the billionth dynamization (ii) of this preparation in 1, 2 or 3 fine pellets moistened with this dilution, as a dose, and this was done successfully for such cures; although the preparation of the higher potencies (iv, vi, vii), and finally the decillionth potency (x), show some advantages, in their quick, penetrating and yet mild action for this purpose; but in cases where a second or third dose (however seldom needed) should be found necessary, a lower potency may then be taken.

Just as the continued presence of the chancre (or the bubo) during the cure shows the continued presence of syphilis, so when the chancre (and the bubo) heal merely from the internally applied Mercury, without any addition of a remedy used for the local symptom, and yet this disappears without leaving any trace of its former presence; it is incontrovertibly sure, that also every trace of the internal syphilis was extinguished at the moment of the completion of the cure of the chancre or the bubo.

But just as incontrovertibly does it follow that every disappearance of the chancre (or the bubo) owing to a mere local destruction, since it was no real cure founded on the extirpation of the internal venereal disease through the internally given appropriate Mercury medicine, leaves to us the certainty that the syphilis remains behind; and every one who supposes himself healed by any such merely local, pretended cure, is to be considered as much venereally diseased as he was before the destruction of the chancre.

The second state in which, as mentioned above, syphilis may have to be treated, is the rare case when an otherwise healthy person, affected with no other chronic disease (and thus without any developed Psora), has experienced this injudicious driving away of the chancre through local applications, effected by an ordinary physician in a short time and without attacking the organism overmuch with internal and external remedies. Even in such a case, - as we have not as yet to combat any complication with Psora - all outbreaks of the secondary venereal disease may be avoided, and the man may be freed from every trace of the venereal miasma through the before-mentioned simple internal cure effected by a like dose of the above-mentioned Mercurial medicine - although the certainty of his cure can no more be so manifestly proved as if the chancre had still been in existence during this internal cure, and as if it had become a mild ulcer simply through this internal remedy, and had been thus manifestly cured of itself.