(1) The totality of symptoms of the patient constitutes the disease for the purpose of a cure.

(2) Drug experimentation on the healthy, so-called drug proving, is the only reliable method to arrive at a knowledge of the effects of drugs.

(3) The curative relation between these two sets of symptomatic facts is the law of similars, Similia Simil-ibus Curantur.

(4) The administration of one single remedy at a time.

(5) The minimum (smallest) dose that will bring about a cure.

(6) Repetition of the dose should cease when marked, improvement sets in.