Picram'nia pentand'ra (?), Cascara Amarga, Honduras Bark, N.F. -- The dried bark of an undetermined species with not more than 2 p.c. of foreign organic matter; C. America. Large handsome tree. Bark, quills 50 Cm. (20') long, 3 Cm. (1 1/5') broad, bark 8 Mm. 1/3' thick, sometimes broken curved pieces, yellowish-brown, grayish lichens, fissured, reddish-brown when cork removed; inner surface brownish, striated, transverse markings, groups of stone cells, odor faint; taste extremely bitter, persistent. Powder, light brown--groups of bast-fibers, crystal- fibers, calcium oxalate prisms, stone cells, medullary ray tissue and parenchyma, starch grains, brown cork, lignified fibers; solvents: water, diluted alcohol; contains picramnine 3 p.c., starch 2 p.c., ash 4.5 p.c. Alterative, bitter aromatic, agreeable flavor. Dose, gr. 15-30 (1-2 Gm.); 1. Fluidextractum Trifolii Compositum, 10.8 p.c.: Prep.: 1. Syrupus Trifolii Compositus, 30 p.c.