Piper angustifo'lium, Matico, N.F. -- The dried leaf with not more than 5 p.c. of stems, flower spikes or other foreign organic matter, yielding not more than 6 p.c. of acid-insoluble ash; S. America -- Andes of Peru, Bolivia. Large soft-wooded shrub or small tree; branches quadrangular, the younger hairy; flowers small, yellowish; fruit small, hard, black, 1-seeded; leaves, usually broken in compressed, matted masses, 10-20 Cm. (4-8') long, 2-5 Cm. (4/5-2') broad, lanceolate, acute, unequal cordate, crenulate, dark green above, tessellated, pale green below, reticulate with prominent midrib and veins, quadrangular-meshed, pubescent; odor distinct, aromatic; taste pungent, pepper-like. Powder, greenish-yellow -- non-glandular hairs, epidermal cells with stomata, secretion cells; solvents: alcohol (50-75 p.c.), boiling water; contains volatile oil 2-3 p.c., artanthic acid, pungent resin, bitter principle, tannin, mucilage--maticin is only a potassium salt. Stimulant, tonic, diuretic, styptic, vulnerary, aphrodisiac (similar to cubeb--mostly due to volatile oil); bronchitis, gonorrhea, menorrhagia, hemorrhoids, diarrhea, dysentery, hematuria, hemorrhage, vesical catarrh, incontinence of urine; locally to bleeding surfaces, owing to the many hairs promoting blood-clot. Adulterations: Leaves of allied species of its own genus, and those of Eupato'rium and Walthe'ria genera -- none being tessellated above or rough and hairy beneath. Dose, gr. 15-60 (1-4 Gm.); 1. Fluidextractum Matico (75 p.c. alcohol), dose, mxv-60 (1-4 cc.). Infusion, 5 p.c., 3j-2 (30-60 cc.); Tincture, 10 p.c., 3j-2 (4-8 cc.).