This section is from the book "A Practitioner's Handbook Of Materia Medica And Therapeutics", by Thos. S. Blair. Also available from Amazon: A Practitioner's handbook of Materia Medica and Therapeutics.
Duboisine is used principally as a mydriatic. It is much stronger than atropine, and is sometimes employed hypodermically in mental diseases. Dose, 1-80 to 1-30 gr. Externally, in 0.2 to 0.8% solution. Homeopathic ophthalmologists use the 3x dilution of Duboisia, or corkwood tree, in the treatment of conjunctivitis, hyperemia of the retina, and for pain over the eyes. Personally, I have had no experience in its homeopathic employment, but from its resemblance to belladonna, which we know relieves capillary hyperemia in small doses, it is reasonable to expect results of a similar nature from this more active drug.