This section is from the "A Handbook of Useful Drugs" book, by State Medical Examining and Licensing Boards.
One hundred c.c. represent 10 gm. colchicum seed in approximately 55 per cent, alcohol; it should assay approximately 0.05 per cent, of colchicin. It is similar to but not identical with the international standard tincture of colchicum seed.
Dosage: 2 c.c. or 30 minims.
In acute gout the dose is from 10 to 30 minims of the tincture once every four hours until some decided evidence of its action, such as nausea or slight purging, is induced. Severe purging should be avoided. Colchicum is of little value in rheumatism.