This section is from the book "Botanic Drugs Their Materia Medica, Pharmacology and Therapeutics", by Thomas S. Blair. Also available from Amazon: Botanic Drugs, Their Materia Medica, Pharmacology and Therapeutics.
Mullein, Verbascum species. The flowers official in nine countries. They are used in the making of "Mulleined Oil." The blossoms, in a closed jar, are subjected to the heat of the sun and are pressed. The extract is combined with oil and, in some formulae, a trifle of alcohol. This preparation is widely used in earache and uncomplicated deafness.
It is dropped into the tympanic canal. The extract of the flowers in 10-drop doses is widely used abroad in the treatment of nocturnal enuresis. It has more of a relaxing and antispasmodic effect than any narcotic action and the activity is due to a volatile oil. It does not seem to be used much in this country. My experience with it leads to the belief that a good preparation is valuable. Many preparations are inert.
The seeds are narcotic and preparations of them have been used in Europe in the treatment of asthma.
Our common mullein, Verbascum thapsus, is official in Belgium and Denmark, but is inferior to the European V. phlomoides, our native plant being little more than a good demulcent due to the large amount of contained mucilage; it is reputed to be antispasmodic and is largely used in domestic practice in the making of poultices.