The purpose of applying bacterial suspensions consists in the generation of an active immunity in the living organism by artificial means. This is achieved by exerting specific and nonspecific stimulation through application of substances into the organism, which cause tissue cells to become stimulated, and the body to form defensive substances. From the type and amount of these formed substances one can then estimate the degree of currently existing immunity. To be sure, it is possible for active immunity to exist under certain circumstances, without proof that humoral bodies are circulating in the blood. However, these substances can immediately reoccur when a new impulse is given to the reactive tissue through a renewed administration of preparations or through specific or nonspecific stimulants.

First Immune Response

Occasionally, a first immune response occurs because the immunologic preparations contain biological substances. Therefore hypersensitivity is possible, in which case the remedy should be discontinued.

Manner of Application of Immunobiological Preparations

The preparations can either be given parenterally, that is, bypassing the gastro-intestinal tract, or (orally) through the intestinal tract.

The parenteral intake guarantees a good and generous immunity. One can inject subcutaneously, intramuscularly and intracutaneously. Finally, also the percutaneous and nasal administration can be used by rubbing the suspension into the skin or dropping into each nostril.

Oral Administration

The oral application of the immunobiological preparations in capsulated form, especially for certain reasons of suitability, for prophylaxis of diseases of the digestive tract, is preferred. Orally taken preparations are intended for reaching immunity and reducing sensitivity toward the relevant infectious pathogen. If a quick and lasting immunization is the target, one can first bring about a basic immunity through a subcutaneous injection. Then, this effect can be maintained and increased through oral intake.

Injection

The injecting process of the injection solution must occur slowly and under sterile conditions. Only disposable syringes are to be used.

Important Comment: The ampules must be shaken before use in order to assure even distribution of the bacterial suspension.

Subcutaneous Injections

Subcutaneous injection is recommended when one targets a lasting effect through slow absorption. Therefore, this type of injection is recommended especially for prophylactic purposes, when one wishes for a maximally long lasting immunity. For the injection, one must naturally avoid locations near the periosteum or nerves and, instead, inject where the correspondingly developed subcutaneous tissue and the musculature beneath it allow for better tolerance. At the beginning of the injection treatment, 0.5 to 1.0 ml 6X are, as a rule, injected into the axillary fold.

Intramuscular Injection

The intramuscular injection is preferred when the goal is to obtain a maximally fast absorption without obtaining a larger general reaction. Therefore, it is highly recommended for therapeutic purposes, especially for suspensions that would cause subcutaneous local reactions because of the stronger active substances contained in them. For the intramuscular injection those locations are to be chosen where the strength of the musculature guarantees a fast absorption. One chooses for this the upper external quadrant of the glutea, and injects deeply intramuscular with 50 or 60 mm needles.

Intracutaneous Injection

The intracutaneous application is less used for stimulation therapy because it is too painful. However, because the skin is generally considered to be an important carrier of immunity, an intracutaneous administration of the suspension can in many cases be of excellent usefulness, particularly when the skin itself is the seat of disease (furunculosis, acne, etc. ). Naturally, one can use only smaller dosages of 0.2 - 0.5 ml (6X) maximally for the intracutaneous injection, due to the size of the wheal formation and the accompanying parallel painfulness. The stretching side of the left upper or lower arm is suitable for this type of application.

Percutaneous Rubbing

Percutaneous rubbing has proven itself well in every case that involves organ stress or nervous irritation and where segmental therapy is appropriate.