Formula - C6H5,Nh2.

Derivation

Phenalgin is a synthetic coal-tar product which may be chemically described as a compound product of the amido-benzine series. The ammonia is liberated in the stomach in a nascent state, and tends to neutralize and antagonize the depression which usually follows the administration of antipyretic products. It occurs as a white powder with an odor of ammonia.

Medical Properties And Physiological Action

It is claimed that it exerts a stimulating effect on the heart, and that in doses of ten grains and upward, a sedative effect is produced in addition to its analgesic actions on the sensory apparatus of the nervous system.

The stimulating effect of the ammonia constituent is first perceived, and this is soon followed by a soothing sensation, due to the gradual subsidence of the painful manifestations. It has no toxic properties.

Therapeutic Uses

It is claimed for phenalgin that it is hypnotic, anodyne, analgesic, antipyretic, antiperiodic. It is employed in all painful affections, such as neuralgia, rheumatism, gastralgia, painful menstruation, headache, effects of dissipation, migraine, influenza, insomnia, etc., for its anodyne and hypnotic properties.

Dose

Of phenalgin, gr. v to xx. It is administered in the form of tablets or in powder.

Dental Uses

Phenalgin is serviceable in facial neuralgia, especially in neuralgias of the fifth nerve, the pain of periodontitis, and alveolar abscess, pulpitis. Dr. A. S. Atkinson states that permanent relief from painful alveolar abscess of two weeks' standing was obtained within one hour after prescribing phenalgin.