In the wide range of convulsive and spasmodic disorders, outside that which we distinguish as epilepsy, bromides are very efficacious. In the convulsions occurring during pregnancy, especially from reflex irritation at the time of parturition, they are more distinctly indicated than in the albuminuric form, but I have seen them also relieve the latter. Peaslee thought them valuable only during the threatening stage, when the urine is scanty, and certainly, the earlier the patients are brought under their influence, the more satisfactory the result. In uroemic convulsion some observers have objected to the use of bromides, but they have been found generally of some assistance in lessening the paroxysm; eliminant and other remedies should be conjoined. The dose in such cases should be large, 1/2 dr. every hour or two. When swallowing is impossible, they act well given in enemata (Gimbert and others: Medical Times, i., 1872, and i., 1874).