This section is from the book "Materia Medica And Therapeutics Inorganic Substances", by Charles D. F. Phillips. Also available from Amazon: Materia medica and therapeutics.
Small doses of the oxide (1/4 to 1/2 gr.), and still smaller ones of the nitrate of silver (1/8 gr.), are usually well borne by the stomach; but the latter salt produces a metallic, bitter taste in the mouth, and, unless well diluted, causes burning sensations in the fauces. In 1/2 to 1-gr. doses it is apt to induce nausea or vomiting, pain, and diarrhoea; headache and vertigo are usual accompaniments. The continued use of smaller medicinal doses impairs the appetite, and may induce intestinal catarrh and hemorrhage. Any amount over 4 or 5 gr. would be usually rejected by vomiting, otherwise it would excite inflammation. After death from toxic doses, the gastro-intestinal membrane has been found soft, eroded, or covered with gray patches. In chronic cases the muscular and mucous coats become hardened and thickened.
1 The chemical formula of the silver-albumen compound seems to vary under different conditions. Lassaigne gives 84.5 per cent. albumen, 15.5 of nitric oxide of silver; Mulder, 16 of the latter in one experiment, 8.9 in another; Krahmer, nearly 12 per cent. Delioux pointed out that the affinity of the nitrate for albumen is greater than it is for chlorine (Husemann).