In true neuralgia, the chloride is often of great value, as Dr. Clifford Allbutt states after observation of fifty cases (Medico - Chi-rurgical Review, January, 1872): it is, however, very nauseous to some patients.

In tic-douloureux, or facial neuralgia, especially if there be a marked rheumatic element and the lower jaw be affected, 1/2-dr. doses of chloride should be given at short intervals, for four doses: relief will probably have then set in if this remedy is going to benefit (Watson: "Lectures," vol. i.). In cases accompanied with heat and swelling, Brenchley recorded marked relief to pain and lowering of temperature under this treatment (Ranking, ii., 1858).

In hemicrania from nerve-prostration it is often curative (Medical Times, i., 1875), and in sciatica I have found either carbonate or chloride valuable, more or less permanently when the pain is worst when the patient is in the standing or sitting posture. In intercostal neuralgia, in anaemic or suckling women, in hepatalgia, and in ovarian neuralgia, Dr. Anstie also reported much benefit from the chloride; and of the latter malady Dr. W. Curran has reported six severe cases marked by acute pain, pyrexia, vomiting, etc., occurring mostly at a period, and accompanied with fulness over the region of the ovary, all much relieved by the chloride in 15-gr. doses, which were given, however, with 5 min. of aconite (Ranking, ii., 1868).