Very successful results have been obtained by using the perchloride locally; for instance, a delicate girl, who had suffered for several years and undergone removal of the nail and most ordinary modes of treatment without relief, was cured mainly by the use of an ointment made with perchloride, and a few applications of the solid compound: the latter gives pain and requires to be almost immediately washed away (Bulletin, 1853). The persulphate has been used in other cases (Medical Times, ii., 1868, p. 257).