Opinions are still divided as to the best time for giving iodides with relation to food.

Dr. Parkes and others recommend them to be taken before meals, in order to prevent decomposition by acids, and to secure dilution with mucus. Some give them at bedtime in effervescence; and again, others find them better borne by a full stomach. All agree that they should be freely diluted, and not taken when there is much starchy food in the stomach, and if there are not febrile or acute gastric symptoms, a bitter infusion or tincture is a good vehicle; in other cases milk is very suitable. Large doses sometimes produce less iodism than small ones (Alt-haus), and arsenic is to some extent corrective of the unpleasant results (British Medical Journal, ii., 1871). Ethereal oil, such as that of peppermint, diminishes the mal-odor of iodoform (Medical Record, 1879).


The iodides sometimes contain iodates of the respective alkalies, and not unfrequently an excess of water, and, after keeping, free iodine is developed to some extent (v. p. 59); but of six chance specimens analyzed all were found pure (British Medical Journal, ii., 1870).