In cases of calculous (uric acid) diathesis, if it be desired to keep the system under the continued influence of alkalies, the salts of soda have sometimes been preferred in weakly dyspeptic subjects, being less depressing than those of potash commonly used. The waters of Vichy have a special reputation in such conditions, and under their influence a urate of soda replaces uric acid in the urine, and is more readily eliminated. The phosphate was especially commended by Liebig and by Golding Bird as a solvent of lithic deposit.

In Albuminuria it has been recommended to supply alkalies freely to the blood in order to lessen the liability to inflammation, and to dissolve fibrinous deposits. It has been taught also that they further the oxidation which is deficient in this dyscrasia, but they can only do so in a slight degree, if at all. Soda, like other alkalies, may be occasionally useful in relieving the dyspeptic symptoms, but is no cure for albuminuria, and its prolonged use is contra-indicated by the tendency to anaemia.