This section is from the book "Materia Medica And Therapeutics Inorganic Substances", by Charles D. F. Phillips. Also available from Amazon: Materia medica and therapeutics.
The gas has been applied in jet to atonic scrofulous ulcers by M. Demarquay, with much advantage.
Gangrene has been attributed by M. Raynaud to deficient oxygenation of tissue, and Langier and other French surgeons have recorded good results from its local treatment by oxygen (Bulletin de Therapeutique, 1863-66). The destruction of tissue has been checked and limited, the swelling subdued, and the neighboring threatened livid tissue restored to its natural color. Dr. Goolden has recorded severe cases of phagedenic ulceration, especially one affecting the throat, which yielded to local application of oxygen, and he has recently written to renew his advocacy of this remedy (Lancet, i., 1866; ii., 1879).