The dried rhizome and rootlets of Podophyllum peltatum, North America.

Fig. 177.   Podophyllum, half the natural size.

Fig. 177. - Podophyllum, half the natural size.

Characters. - In pieces of variable length, about 1/5 of an inch thick, dark reddish-brown externally, whitish within, breaking with a short fracture. At intervals of about two inches the rhizome is thickened, and from each swollen part or joint a number of pale brown rootlets spring. These are brittle, and many of them break short off close to the rhizome, leaving little round white spots which help to distinguish podophyllum easily from other roots. Powder yellowish-grey, sweetish in odour, bitterish, subacrid and nauseous in taste.

Composition. - Its most important constituents are podo-phyllin, which is a resinous substance, and berberine, which is a yellow alkaloid (p. 839).

Officinal Preparations Of Podophyllum

B.P.

Dose.

Podophylli Resina ..............................................................

1/8-1 gr.

U.S.P.

Dose.

Resina Podophylli .............................................................

1/8-1/2 gr. (0.008-0.03 gm.)

Abstractum " ..................................................................

5-10 gr. (0.33-0.67 gm.)

Extractum " .................................................................

1-3 gr. (0.06-0.2 gm.)

" " Fluidum .............................................

5-15 min. (0.3-0.9 c.c.)