The dried leaves of Erythroxylon Coca.

Characters. - Shortly stalked, oval or lanceolate, of varying thickness, one to two inches or more in length, entire, usually blunt and emarginate, quite smooth; midrib prominent, with numerous faint freely anastomosing lateral veins, and on each side of the midrib a curved line extends from base to apex; green above, somewhat paler beneath. In commercial specimens the leaves are more or less broken, and frequently yellowish-green, yellowish-brown, or brown, and in rare cases the curved lines are indistinguishable. Odour faintly tea-like, especially when bruised; taste somewhat bitter and aromatic.

Dose. - 1/2to 2 drachms. Preparations.

B.P.

Dose.

Cocainae Hydrochloras...............................................

1/5-1 gr.

Extractum Cocae Liquidum (1 in 1)...........................

1/2-2 fl. dr.

U.S.P.

Extractum Erythroxyli Fluidum.....................................

1-4 fl. dr.

Composition. - This drug contains the alkaloids cocaine, ecgonine, and hygrine, and a volatile constituent which gives a pleasant fragrance to the fresh leaves. Different specimens of the leaves vary greatly in their strength. Leaves which have been long kept contain less of the active alkaloid than the fresh leaves.