This section is from the book "Materia Medica Pharmacy, Pharmacology And Therapeutics", by W. Hale White. Also available from Amazon: Materia Medica Pharmacy, Pharmacology And Therapeutics..
Chirata. - Synonym. - Chiretta. The entire plant, Swertia Chirata Hamilton (nat. ord. Gentianeae).
Mountains of Northern India.
Root nearly simple, about 7 cm. long; stem branched, nearly I meter long, slightly quadrangular above; containing a narrow wood-circle and a large yellowish pith. Leaves opposite, sessile, ovate, entire five-nerved. Flowers numerous, small, with a four-lobed calyx and corolla. The whole plant smooth, pale brown, inodorous, and intensely bitter. Resembling Chirata. - Lobelia, which is not bitter.
The chief constituents are - (1) Chiratin, C26H48O15, an active, bitter principle, as a yellow, hygroscopic powder. (2) Ophelic Acid, C13H20O11 with which it is combined. No Tannic Acid is present.
Dose, 1/2 to 1 dr.; 2. to 4. gm.
1. Extractum Chiratae Fluidum. - Fluid Extract of Chirata. By maceration and percolation with Alcohol and Water, and evaporation. Dose, 1/2 to 1 fl. dr.; 2. to 4. c.c.
a. Tinctura Chiratae. - Tincture of Chirata. Chirata, 100; by maceration and percolation with Alcohol and Water to 1000. Dose, 1/2 to 2 fl. dr.; 2. to 8. c.c.
Chirata has the same actions and uses as gentian, calumba and other bitters. As it contains no tannic acid, it can be given with iron. It is more frequently used in India.
 
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