This section is from the book "Materia Medica Pharmacy, Pharmacology And Therapeutics", by W. Hale White. Also available from Amazon: Materia Medica Pharmacy, Pharmacology And Therapeutics..
A gum resin obtained from Garcinia Hanburii Hooker filius (nat. ord. Guttiferae).
Anam, Camboja and Siam.
In cylindrical pieces, sometimes hollow in the centre, 2 to 5 cm. in diameter, longitudinally striate on the surface; fracture flattish-conchoidal, of a waxy lustre, orange-red; in powder bright yellow; inodorous; taste very acrid; the powder sternutatory.
It is partly soluble in Alcohol and in Ether.
The chief constituents are - (1) A brilliant yellow Resin, Gambogic Acid, 65 to 80 per cent. (2) Gum, 16 to 26 per cent. This is soluble, so that an emulsion of Gambogic Acid is formed with water.
Starch, woody fibre.
Gamboge is contained in Pilulae Catharticae Composite.
Dose, 1 to 5 gr.; .06 to .30 gm.
Gamboge is a drastic, hydragogue purgative, causing much griping, and, in large doses, great irritation of the alimentary canal. Most of it passes in the faeces, but some is absorbed, causing the urine to be yellow. It is slightly diuretic.
It is not often prescribed, as it is uncertain, and gripes considerably. It should never be given alone. It has been used as an anthelmintic.
 
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