This section is from the book "Materia Medica Pharmacy, Pharmacology And Therapeutics", by W. Hale White. Also available from Amazon: Materia Medica Pharmacy, Pharmacology And Therapeutics..
Salophen. (Not official. ) - C6H4(OH)Co2c6h4nhcoch3=270.40. Synonym. - Acetylparamidophenol Salicylate.
From Paranitrophenol Salicylate by a complicated process, and purifying by crystallization from Alcohol.
Minute white scales, free from odor or taste. It contains 50.9 per cent. of Salicylic Acid.
Almost insoluble in water; freely soluble in Alkalies, Alcohol and Ether.
Dose, 5 to 15 gr.; .30 to 1.00 gm.
In a warm alkaline solution salophen is broken up into salicylic acid and acetylparamidophenol, the latter being harmless. It is decomposed in the intestines, even when given hypoder-matically. It is used as a substitute for salicylic acid in acute rheumatism, and as an intestinal antiseptic. It is probably quite as efficient, and much safer than salol. The fact that it is tasteless renders it easy of administration.