Under this title phenyl-methyl-acetone has been brought forward by Popof and Nencki as a representative analgesic and hypnotic. Dujardin-Beaumetz and pupils have followed with clinical investigations, in which the claims made have been largely confirmed.

It is a limpid, colorless liquid, odorless, but has a pungent taste. The dose is 2 to 5 minims. It should be administered in capsules, or made into an emulsion.

Hypnone has been successfully employed in the treatment of painful affections of the fifth nerve, tic-douloureux, rheumatic disturbances of the dental branches of the same nerve, in hemicrania, and similar disorders. It is applicable to the treatment of other neuralgic affections and so-called rheumatic muscular troubles, as lumbago, sciatica, etc.

Hypnone also is a moderator of reflex actions, and has been utilized in the treatment of epilepsy, chorea, and allied diseases. As respects epilepsy, it is more especially the nocturnal affection to which it is applicable. Asthma—the spasmodic variety—whooping-cough, singultus, are also disorders amenable to its action. Such spasmodic and painful affections as hepatic and renal colic, flatulent colic, etc., are conditions to the treatment of which it may be successfully applied.