The dried flower-heads of Artemisia pauciflora, of Asia Minor. The active principle is santonin, and there is also a compound volatile oil resembling camphor in its action.

Santonin is an anthelmintic, acting especially on the ascaris lumbricoides, or round worm. In overdoses it produces disturbances of vision and of consciousness. Objects appear at first to be blue, then yellow. There are tremors, aphasia, and sometimes convulsions. The respirations become feeble, and the pulse is reduced.

It is necessary, in giving it, to watch its action, that these symptoms may be avoided.

It is excreted by the bowels and by the kidneys, and discolors the urine, making it saffron or reddish. There have been numerous cases of fatal poisoning among children from santonin. Alarming symptoms have been caused by gr. ii. in a child eight years old, and a dose of gr. ii. to a child of five years caused death.

Santoninum. Santonin

Average dose, gr. i.-0.06 Gm.