A. Severe pruritus; (H.G.P.).

Scarlatinoid eruption, Fournier.*

C. Pityriasis, eczema, herpes, impetigo in children, Neligan, 44, 3111. Lupus, Houghton.+

Psoriasis, 81, 23. Pruritus; (H.G.P.). Syphilis.

D. Syphilis, acne, infiltrations, lupus, 209.

Remarks

I have met with two cases in which pruritus appeared to result from the ingestion of the protoiodide of mercury. The first was a gentleman suffering from syphilis, to whom I gave a fifth of a grain of protoiodide three times daily. At the end of ton days he returned complaining of severe general pruritus accompnied with urticarial wheals. I discontinued the mercurial, and prescribed for the (supposed) urticaria. Ho returned & week later, stating that the itching had disap-peared. He resumed the protoiodide, and had a renewal of pruritus. A change was then made to the bichloride, which he took without further inconvenience. A few months later a return to the protoiodide was followed by a renewal of the pruritus. Since then I have been on the lookout for this complication, and have met with it once in a woman in one of my syphilitic wards at the Charity Hospital.

* Hallopeau, op. cit.

+ Article in Cyclopedia of Practical Medicine. London, 1834, Vol. III., p. 180.

I have treated successfully one case of obstinate general pruritus with this drug in small doses. In other cases of pruritus in which I have tried it has not proved of service.