As there is but one agent which I could place strictly under the spinal stimulants; nux vomica, namely, and other vegetable products characterized by the presence of strychnia; so there is but one which I can attach to the present class - the newly discovered Bean of Calabar. it is true that there are several medicines which act as sedatives of the spinal centres; yet there is none other which is exclusively so, or which does not possess properties that classify it with other categories, and especially with the nervous and cerebral sedatives.