The doctrine of the unity of disease, as advocated by Thom-sonians, has not generally been understood, and therefore the medical faculty have endeavored to bring the Thomsonian system into disrepute by ridiculing it. We do not say every form of disease is characterized by the same symptoms, or is located primarily or principally on the same organ; but that for the purpose of applying medicine safely and scientifically, a division of disease into classes, orders, and kinds, is not necessary, neither is it possible. When we transgress the laws of nature by constantly overloading the stomach, the effect is general, every organ is more or less deranged and debilitated, consequently not capable of performing its functions. To what organ should medicine be applied to remove the cause and effect of disease? Would not the only rational course be to remove the first cause by taking food in a proper quantity and quality, and then, by general stimulants and relaxants, arouse the different organs to action to throw off the morbid accumulations, and thereby relieve nature by removing the obstructions to her free operations ? Let the form of disease or symptoms be what they may, the business of the physician is to remove the obstructions to nature's efforts, and assist her in her operations. We may as consistently divide hunger into a thousand different kinds, and prescribe one particular article of food to nourish one portion of the system, and another article to nourish another part, as to prescribe a medicine to remove disease from a particular portion of the system, without having its natural effect on the whole system. An experience of fifty years by millions of patients afflicted with every conceivable form of disease, has sufficiently tested and established the fact, that a Thomsonian course of medicine, judiciously administered, is adapted to the cure of every form of disease, that is curable; although in many cases it may not be necessary to resort to it, as something more mild and pleasant in its operation will frequently accomplish the object in the early stage of disease; neither is it necessary to administer it when the powers of nature are so far exhausted as to render a recovery impossible. On this one fact does the safety of the Thomsonian system depend in the hands of the people--that disease, wherever located in the human system, whatever its form or the symptoms by which it is characterized, may be successfully treated on general principles, with remedies operating in harmony with the laws of nature. So that the mother may administer to her child, the husband to the wife, and the wife to the husband, with the most unshaken confidence; and thereby avoiding the quackery for which the present age will ever be memorable