Elixir of citrate of ammonium with bismuth, 16 fluidounces.

Strychnine, 1 1/4 grains.

Acetic acid, a sufficient quantity.

Triturate the strychnine in a mortar, cautiously adding acetic acid until the alkaloid is dissolved, then add the elixir of citrate of ammonium with bismuth.

Each fluidrachm (teaspoonful) of the finished elixir contains two grains of citrate of ammonium and bismuth, and about one-hundredth of a grain of strychnine as the acetate of that alkaloid.

Strychnine is incompatible with alkaline solutions, and if a precipitate should occur while the elixir has an alkaline reaction, care must be taken that this precipitate is thoroughly mixed with the liquid before each dose is administered, inasmuch as the ammonio-citrate of bismuth is incompatible with an acid, this elixir must have an alkaline or at least a neutral reaction. However, although one and one-fourth grains of strychnine refuse to dissolve in sixteen fluidounces of water, it seems that the menstruum composing this elixir has the property of holding in solution the strychnine, even though it (the elixir) is alkaline, and thus the general incompatibility of the constituents is overcome.