Delirium Tremens. It is very probable that the auto-toxins play an important part in the etiology of delirium tremens. This disease is primarily a toxic state due to alcoholic saturation, but when renal and hepatic functions are disturbed the autogenous poisons are added. The possibility of these insufficiences is two-fold. First, that the alcoholic poison has caused interstitial nephritis and a loss of functional liver mass through fatty degeneration or cirrhosis; secondly, that alcohol has occasioned gastro-intestinal catarrh with general perversion of alimentary function which predisposes to the formation of auto-toxins. It is a clinical fact that cases of mania a potu which have good digestion and functionally active kidneys do well, while those in which the emunctories are faulty do not do as well and are likely to end fatally, (49).

Eichorst attributes the delirium which occasionally accompanies heart disease with edema, to toxic bodies derived from the edematous fluid, and the failure of the kidneys to eliminate the same, (50). In this condition there is at first somnolence which soon gives way to loss of consciousness interrupted by delirium and violent mania. The respirations are deep and frequent, the face flushed, and the clinical picture resembles that of delirium tremens.

Night Terrors of children with their numerous concomitant symptoms may be considered as the result of CO poisoning. In substantiation of this view it appears that pharyngeal obstruction prevents proper oxygenation of the blood, that the symptoms are identical with those of known CO poisoning, and that the disorder disappears after the obstacles to respiration and hematosis are removed.