Object Of The Investigation

To determine what changes, if any, are induced in the osseous system by an excessive meat diet (ox-flesh).

Method Of Observation

Material employed:

(a) Newly-weaned rats.

(b) Young rats of meat-fed mothers.

(a) Diet of ox-flesh commenced on weaning rats, controls being obtained from equal number of same litter fed on bread and milk. Examinations at varying ages from one month to three months.

(b) Young of meat-fed mothers fed when weaned on meat flesh. Examinations at varying ages from one day to three months. Controls of corresponding age fed on bread and milk.

Nature Of Changes Noted. Macroscopical

1. General softness of whole osseous system.

2. Increased vascularity.

3. Bread-like prominences at costo-chondral junctions and less frequently on ribs themselves.

4. Curvatures of the spine and long bones.

1 A. Dingwall Fordyce, M.D., Journal of Physiology, vol. xxxiv.

Microscopical

1. Evidences of defective bone development, both intra cartilaginous and intra-membranous.

2. Markedly increased vascularity.

3. Changes in the bone-marrow.