Amphipolis (now Jenikeui), a city of ancient Macedonia, on the Strymon (now Struma, or Kara Su), near its mouth. It was originally called Ennea Hodoi (Nine Ways), and held by the Thracian Edonians, and received its historical name from an Athenian colony which occupied it in 437 B. C. It was besieged by the Lacedaemonians under Brasidas during the Peloponnesian war, and compelled to surrender to them (424). Later it fell into the hands of Philip of Macedon, and under the Romans it was the capital of a Macedonian district. In the middle ages it was called Po-polia. There are few remains of the town.