This is frequently seen as a further stage of the condition just mentioned, and is a special feature in acute yellow atrophy to be presently described. It is also usually present in pernicious anaemia. A more localized fatty degeneration is met with in consequence of local affections of the liver, as in passive hyperemia, but more especially in cirrhosis of the liver. It is characterized by the presence of minute fat granules in the protoplasm of the cells.