Cancer is not very uncommon. It occurs chiefly as an ordinary glandular carcinoma, but also as a cylindercelled tumour. Sarcoma also occurs. Wolfler has observed, besides the ordinary round-celled tumour and spindle-celled forms, a true giant-celled sarcoma. In a case of round-celled sarcoma observed by the author there were two large cysts, and the tumour extended down into the chest as far as the pericardium. It also incorporated the anterior wall of the trachea.

Fig. 384. - From section of secondary tumour in bone in case of goitre, x 300.

Literature

Inflammation - Kochek, Deutsche Zeitschr. f. Chir., x., 1878; Brieger, (Diphtheria) Charite-ann., viii., 1883; Jeanselme, Gaz. des Hop., 15,1895. Tuberculosis - Chiari, Med. Jahrb., Wien, 1878; Brun's Beitrage z. klin. Chir., x., 1892 (literature). Syphilis - Barth et Gombault, Progres med., 1884. A very full account of Goitre and Tumours, with many illustrations by Wolfler, in Langen-beck's Arch., xxix., 1883; Virchovv, Krank. Geschwiilste, iii.; Gutknecht, Virch. Arch., xcix.; Bircher, Der endemische Kropf, 1883; M'Kenzie, Glas. Med. Journal, ii., 1899; Grasset, (Hrematozoa) Brit. Med. Jour., ii., 1898. Goitre urifA secondary tumours - Cohnheim, Virch. Arch., lxviii., 1876; Morris, Path, trans., xxxi., 1880; Coats, ibid., xxxviii,, 1887. Tumours - Bircher, in Volkmann's Sammlung, No. 222; Coats, Catal. of Pathological Museum, Western Infirmary.