Constituents of the blood: - (1) Plasma; (2) Red corpuscles; (3) Leucocytes; (4) Bizzozero's third corpuscle. I. General hyperemia, Plethora; produced artificially by Transfusion of blood; Plethora as a pathological condition. II. General anaemia; (1) Causation; (a) From destruction of red corpuscles, haemorrhage, hemoglobinuria; (b) From defective formation. (2) Character of the changes in the blood in oligemia; in pernicious anaemia; in chlorosis; in secondary anemias. (3) The bone-marrow in anaemias. (4) Secondary changes in anaemias. IV. Leukaemia, Causation obscure; changes in blood and nature of the disease; condition of spleen; bone-marrow; lymphatic glands; liver, kidneys, etc.

THE blood is to be regarded as a tissue which is being continually changed by loss and renewal of its constituents. It is a fluid in which are suspended red and white cells or corpuscles, and it is a vehicle by which the nutritious material required by the tissues, and the oxygen necessary for their respiratory processes are conveyed; the former function being performed by the liquor sanguinis, and the latter by the red corpuscles. It also carries off to their proper places of excretion the products of tissue change, and the carbonic acid resulting from the respiratory process in the tissues.