This section is from the book "Research In Physiopathology As Basis Of Guided Chemotherapy With Special Application To Cancer", by Emanuel Revici. Also available from amazon: Research In Physiopathology
Nasal pH was measured using a portable Beckman pH meter and a glass electrode small enough to penetrate deep into the nose. In a research made with N. Buchanan it was found that valid data could be obtained only if the electrode touched the turbinate, otherwise marked differences in values were noted.
Fig. 211. The relationship between daily changes of the nasal and urinary pH shows opposite variations.
In a simplified method, cotton applicators were soaked in Guillaumin indicator solution with methyl red and bromothymol blue and left to dry. They were easily introduced to sufficient depth in the nose and left in place for at least two minutes. Color of the wet spots was checked with a colon metric scale. Data obtained with glass electrode and colormetric applicator were found to coincide closely.
Two offbalances could be seen, one with the pH elevated sometimes even above 8. Figures 209 and 210 show curves of the offbalance in two patients. It is interesting to note that the changes in the nasal pH values parallel these seen at the level of lesions and are opposite to those concomitantly occurring in the urinary pH (Fig. 211) which parallel those of the titrimetric alkalinity of the blood.