This is of two kinds, the distinct, and con-fluent. The distinct begins with chilness and shivering, intense heat, a violent pain in the head and back, and an inclination to vomit. Epileptic fits in children, if breeding of the teeth is over, is a sign the small-pox is at hand. On the fourth day the spots appear, which are at first reddish and spread themselves over the face, neck, breast, and the whole body. Then there is a pain in the threat, which increases as the pustules grow turgid.

On the eighth day, the spaces between the pustules grow reddish, and are affected with a tensive pain; the eye-lids are puffed up and close the eyes. Next after the face, the hands begin to swell, and the fingers are distended; the pustules of the face, before smooth and red, begin to grow rough and whitish, and throw out a yellow matter in colour like honeycomb. The inflammation of the face and hands being now at the height, the spaces between the pustules are of the colour of damask roses; and the more mild the disease is, the greater is the likeness. The pustules about the face grow more rough and yellow as they ripen; but on the hands and other parts of the body, they grow more white and less rough. On the eleventh day, the swelling of the face and inflammation disappear; the pustules being ripe, and of the size of a large pea, grow dry and fall off. On the fourteenth or fifteenth day, they perish entirely; except some obstinate pustules on the hands, which continue a day or two longer, and then break. The rest come off in branny scales. Throughout the whole course of this disease, the patient's body is either wholly costive, or he goes to stool but very seldom.

Thus, the first state of the disease, from the time of inva-sion, till the appearance of the spots, is four days. The second state or time of eruption, continues from the fourth day till the seventh. The time of maturation, or ripening, is from the seventh till the eleventh. The fourth state, or time of exficcation, or drying of the pustules, is from the eleventh to the fourteenth or fifteenth.

In the confluent forty all the symptorns are more violent; on the third day, and sometimes before, the spots appear, and the sooner the more they will run together. When there is a very violent pain in the loins, like the gravel; in the fide, like a pleu-risy; in the joints, like a rheumatism; in the stomach, with sickness and vomiting; the eruption may be retarded till the fourth or fifth day. But when this happens, the symptoms do not abate as in the distinct sort, but the fever and other complaints continue many days after. As the fever increases, the pustules do not arrive to any considerable height, but are entangled with each other in the face, appearing like a red blister, and covering all the countenance, which swells sooner than in the distinct kind. Afterwards they appear like a white skin glued to the face, and are not much higher than the surface.

After the eighth day, this skin or pellicle grows more rough, and of a dusky colour; the pain of the skin becomes more intense; and in the more cruel kind they do not fall off in broad large scales, till after the twentieth day. The browner the pustules are, they are worse, and the longer in falling off; but the more yellow they are the less they run together, and the sooner they fall off.

When the skin or pellicle falls off, there is no roughness on the face, but branny scales come in their room, of a very cor-rosive nature, which leave pits behind, and sometimes ugly scars.

The danger of the disease is to be estimated from the number and multitude of the pustules on the face alone. The patient is in most danger, in the common confluent sort, on the eleventh day from the first attack; in the more crude the fourteenth, and in the most crude the seventeenth.

In the milder small pox, the fever is separated by two perfect intermissions; and though they run into each other in the malignant sort, yet the traces of the limits may be discerned by some degree of remission. Thus, there is a fever of despuma-tion and another of maturation, to which may be added a third of retrocession, commonly called the secondary fever; for the very moment the bases of the pustules loose their fiery colour, this fever kindles like a flash of lightning.

Some divide the small-pox into the simple, and the malignant. The simple is, when the eruption is attended with a slight fever of short duration; the malignant is, when the eruption appears with a malignant fever, and the pustules hardly come to any tole rable degree of ripeness. This has pustules of three sorts: the crystalline, which are almost transparent and like bladders filled with thin water. The warty: these contain no fluid and are like warts; they are peculiar to the distinct sort. The bloody: these are sometimes small tubercles filled with a black-ish blood, as if the skin had been pinched with nippers, and are attended with purple and livid spots. Sometimes the pu-stules, after the third or fourth day of their coming out, become livid and a little bloody with black spots over all the body, which forebode death in a day or two; in this cafe the blood will flow out from every part of the body, such as the mouth, nose, eyes, and urinary passages In the cure, when the pulse is rapid, full, tense, the breathing hot, short, and laborious, the urine high, the thirst great, the tongue dry and soul, the pain in the head, back, loins, and limbs exceeding acute, there can be no doubt about the neces-sity of bleeding.

But bleeding is by no means proper, when the disease comes on with the usual symptoms of a flow nervous fever, when the patient has been drooping for some time, and the fever is low, the spirits sunk, the pulse weak, quick, and fluttering, the countenance pale and fallen, the urine crude and thin, no great thirst, no great heat, a continual giddiness and heaviness of the head, with tremblings, a perpetual nausea and puking, weak-ness and weariness, which ends in the small pox of a very bad sort, being pale, crude and pitted, never rising well, but continuing flat and flaccid, or running together in large watery blisters, full of thin indigested matter, and so remaining to the last, while in the face, from a deadly pale colour like a corps, they turn to a ghastly black, if the patient live long enough; and even then, they generally prove fatal at last.