Sometimes, as was observed above, the small pox is attended with a malignant spotted fever, with profuse bleeding, bloody and gangrenous pustules; even when the pox are very few and distinct. Each of which particular cafes require a particular method, and a regard to the diseases to which they are related.

In the first: cafe, besides the symptoms already mentioned, if an acute pain in the head, redness of the eyes, throbbing of the carotid and temporal arteries, denote the approach of a phrenzy, it will be necessary to bleed in the soot, as well as the arm, which generally has an admirable effect. After bleeding, a vomit should be given, if the stomach abound with phlegm or bile, or be loaded with food unseasonably taken. Otherwise before the eruption of the pustules, a purge may be prescribed with the infusion of fena and manna, or with manna alone, especially for children. If in the course of this disease the patient should be costive, his body is to be opened with a clyster every second or third day. Likewise, under these cir-cumstances, the fever powder of Dr. James has always had salutary consequences, when given in time, and has disposed the patient to go through every if age of the disease, free from those alarming circumstances which frequently attend this disease, when unassisted with so powerful a medicine.

Moreover, the following powder has a tendency to keep the inflammation of the blood within due bound., and to assist the ex-pulsion of the morbific matter through the skin: "Take of com-"pound powder of crabs claws, half an ounce; of purified nitre, "two drams; mix and matte a powder." Half a dram of this may be given to an adult three or four times a day, diminishing the quantity for children in proportion to their age. When fever runs high, equal quantities of the ingredients may be preferred, and the patient's drink may be sharpened with spirit of vitrial. When there is a reaching to vomit, it may be appeased with a spoonful of the juice of lemons', and a scruple of the salt of wormwood.

When the eruption of the pustules are completed, the patient may take an ounce of the syrup of white poppies in the evening; and when the inquietude is great, it may be repeated in the morning. On the tenth day from the invasion, at night, the dose may be increased to an ounce and a half, and an ounce in the morning, and soon, till the patient recovers, unless there be a delirium, for then it is not convenient. Eighteen drops of liquid laudanum may be given instead of an ounce of the syrup. But not when there is a shortness of breath, or the patient is like to be choaked with viscid slime, unless oxymel of squills be given at the same time, or rather the fleam hereafter mentioned. When the vesicles do not fill, give from ten grains to forty of the peruvian bark in syrup of orange peel, diluted with nutmeg water, every fourth or fifth hour; children may take it in a clyster.

But in order to prevent bad symptoms, on the day before the face is expected to sink, the arms and legs must be wrapt up lightly in a suppurating cerate; for instance, the yellow cerate, which is made by melting an ounce of bees wax with half a pound of yellow basilicon. It must be spread on linen roll and tacked together so as to make one continuous plaster. This facilitates the translation of the acrid serum from the face and head to the limbs, promotes the suppuration of it when it is translated, and presently removes the burning pain, which is insupportable at this time of the disease. Thus, this dangerous period may be past over without any alarming symptom.

Some persons, otherwise strong, fall into a vast dejection of spirits at the time of the seizure with the small pox through fear, and then a little blood should be taken away as early as possible, which mull be repeated if necessary, but not too large a quantity at once. Likewise something cordial may be given to chear the heart, and blisters must be applied to prevent the patient from finking under the disease; especially when there is a rawness, foreness, or great heat of the mouth and throat, with a sharp rheum, or a stoppage of the nostrils, with frequent sneezing and a tickling cough. When the matter of sa-livation is very viscid and clogs the throat, the best method is to boil marsh-mallows, myrrh, and honey in a sufficient quantity of water and vinegar, and then transmit the steam into the patient's mouth, through a glass or tin pipe, of such a shape and length as is suitable to the person while he lies down. This has been sound by long experience to be very salutary.

When the small pox has relation to the nervous fever, some easy cordial nervous medicines will be necessary, such as sack-whey, wine and water, and in the more low depressed cafe, wine alone. Blisters may be now employed, and stimulating cataplasms to the feet.

In the malignant sort of the crystalline small pox, the water of the pustules can never be brought to laudable suppuration, and therefore it will be proper to give from a scruple to half a dram of nitre, three or four times a day, in small wine, to carry off the grosser humours. And towards the end of the disease, the patient may be allowed a little canary to comfort the heart. The flux of the humour into the pustules may be promoted by the cordial confection, or a scruple of the compound powder of crabs-claws with three grains of saffron, or the bark in the manner above mentioned, or rather the following tincture of it, which is an excellent medicine: "Take of the Peruvian "bark, two ounces; of the yellow part of orange peel, an "ounce and a half; of Virginian snake-root, three drams; "of saffron four scruples; of French brandy, a pint and a "quartern; put them together into a bottle, stop it close, and "let it stand for three or four days, and then strain off the "tincture." The dose is from a dram to half an ounce, every fourth or sixth hour. You may also give the plain spirit of hartshorn. The patient may be allowed a dish of coffee now and then, with a little thin milk in it.

Betides, these on the fifth or sixth day of the eruption, blisters are to be applied between the shoulders, and to the arms and legs, to discharge the ferosities, and to help the fever.

The warty small-pox is more dangerous than the crystalline, because the matter of the disease is too thick, and will neither suppurate nor pass off by urine. Here the above cordial medicines come in play and blisters also : but there are little or no hopes from any method.

In the bloody small-pox those medicines are heft, which by their styplicity thicken the blood, and prevent its breaking through the smallest arteries. In this cafe butter-milk will lend great assistance, especially as it is an enemy to putrefaction. As also, Peruvian bark, alum, and oil of vitriol; but more particularly equal quantities of roch alum and dragon's blood melted together and beaten into a powder. A scruple or half a dram of this made into a bolus with conserve of roses, is a proper dose. It may be repeated in a few hours in dangerous bleedings. In less urgent cafes, a dram of the Peruvian bark may be given every sixth hour; or five or six spoonfuls of the tincture of roses, may be taken several times a day : and the patients drink may be sharpened with it, when there are purple or black spots interspersed among the pustules. When there is a delirium, blisters may be safely applied.

About the ninth or tenth day from the eruption a putrid fever, common called the secondary fever, may come on, and it has been common to give gentle purges; as also to bleed when the heat is too great, and the patient's strength will bear it, not omitting blisters. But the patient may be cured without blistering or bleeding, if he takes the absorbent nitrous powder, of compound powder of crabs-claws with nitre, before mentioned; as also analeptics and plenty of diluting absorbent liquors. The bark has likewise good effects in mitigating the secondary fever, unless the lungs be fluffed, and then it is to be omitted.

There are accidents in the small-pox which do not always occur, and therefore it will be necessary to mention them. Sometimes the patient is seized with convulsions just before the eruption, which in children is no bad sign; and then no blood must be taken away, but a blister may be laid to the neck, and a plaster with equal parts of the cephalic and blistering; plaster maybe laid to the feet Inwardly he may take wild valerian-root, Ruffian castor, and the spirits of hartshom.

When there is an entire suppression of urine, the patient's body may be opened with a clyster, and he may take Glauber's (alt, which is diuretic and laxative; or rather, which is the bell medicine, salt of amber, if it can be had genuine. The dose is from eight grains to twenty.

When the eruption appears without much fever and pain, and the pustulcs do not ripen, it will be succeeded with a fever, attended with restlessness of body, anxiety of mind, difficulty of breathing, and a delirium. In this cafe warm medicines should be given to increase the fever at first, and afterwards to promote suppuration. For this last intention, "Take of Virgi-"nian snake-root, twelve grains; of contrayerva-root, six "grains; myrrh and saffron, of each five grains; mix and "make a powder." This may be taken every four or five hours, in any proper vehicle. But Peruvian bark, as was observed before, is excellent in this cafe, and particularly the tincture of it above mentioned. If the patient is low, a blister will be necessary.

When the matter of infection is over abundant, it will produce a spitting on the first day of the eruption in adults, and in children a looseness almost throughout the whole disease. If in adults the spitting does not succeed to our wishes, it should be promoted with gargles made with a decoction of mustard-feed and pepper mixt with oxymel: for in the confluent and malignant fort, it ought to continue to the end of the disease.

When a woman with child miscarries in the small-pox, and the flux of the lochia is too large, she must take the same remedies as in the bloody small-pox. If a woman's monthly e-vacuations appear in this disease, they rather afford relief than threaten danger, unless the discharge is so great as to weaken the patient, and then she must take the same remedies as in the bloody small-pox.