Salicinum, Salicin. Antirheumatic, antiperiodic, and bitter tonic. Large doses (20 to 30 gr.) are of value in acute rheumatism. It is safe in large doses, and while not so potent as the salicylates, can be used when they are contraindicated. As an antiperiodic, it is used in chronic forms of malaria, in 10 to I5 gr. doses. In small doses (2 to 5 gr.) it is a gastric tonic of value in chronic atonic dyspepsia with a tendency to diarrhea.