As in the majority of cases these are given by the patient himself, he should be instructed as follows: First, he should always urinate before injecting, to so far as possible wash out the urethra and so reduce the chance of carrying the infection backward by the injection. A suitable syringe holds about 20 c. c. and has a eone-shaped nozzle, preferably of soft rubber.

Having filled the syringe with the solution to be used, he should hold the penis in the left hand, the glans between the forefinger and thumb, which support it from underneath. Hold the syringe in the right hand between the thumb and second finger and manipulate the piston with the forefinger. Next introduce the nozzle into the meatus, and if the thumb and forefinger of the left hand are brought together they will close the meatus down upon the nozzle and prevent leakage during the injection. Depress the piston slowly until the urethra is fully distended. The syringe may now be removed, the left forefinger and thumb closing the meatus and so retaining the injection as long as may be required. This will depend upon the strength of the solution used and the age of the inflammation, usually from one to three minutes. The medicaments used are antiseptic and astringent, and those most employed are zinc sulphate, silver nitrate, various silver organic salts, potassium permanganate, hydrogen peroxide, ichthyol, and simple alkaline solutions.

If deemed advisable the Valentine prolonged irrigation with weak solutions may be used.