The Phosphates are ingredients of most of the animal and vegetable foods, and a sufficient amount of phosphorus is, under normal conditions, appropriated by digestive action for the supply of the system. Every part of the body contains phosphate of lime ; and rickets, softening of the bones and defective teeth result when too little is supplied during the formative period. The blood, saliva, gastric juice, urine, milk and the entire intercellular fluid contain phosphate of lime in solution. When this agent is administered by the stomach, diffusion into the blood results as a consequence of its being to some extent soluble in lactic and hydrochloric acids; hence it is very essential to the nutrition of the body, and small doses are as effective as large ones, as all in excess of the quantity soluble in the acids of the stomach is not appropriated, but passes off or forms concretions in the intestines. Phosphate of sodium is also a constituent of the blood, and by removing morbid states of the mucous membrane it promotes digestion and improves nutrition and the tone of the nervous system. Large doses, on the other hand, when administered in health, will impair digestion. Phosphorus exists generally as a phosphate, and has a strong affinity for oxygen, compounds being rapidly formed in the stomach; but some of it may enter the blood uncombined. It is a powerful irritant poison, the dose being no larger than 1/100 to 1/20 of a grain.

The preparations of the Phosphates and Phosphites are: Syrupus Calcii Lacto-phosphatis. - Syrup of the lacto-phosphate of lime. Dose. - Phosphates And Phosphites 1283 to (See Syrup of lacto-phosphate of lime.)

Compound Syrup Of The Phosphates

Each drachm contains 33 two and a half grains of phosphate of iron and one grain of phosphate of lime.

Sodii Phosphas - Phosphate Of Sodium

In the form of large, colorless, transparent prisms, with a cooling saline taste, feebly alkaline and no odor, and a slightly alkaline reaction. Soluble in six parts of water at 6o° F., and in two parts of boiling water.

Dose

Dose 1285 to Calcii Phosphas Pracipitatus. - Precipitated Phosphate of Lime. In the form of a white powder, with no taste or odor, and insoluble in water or alcohol. Dose. - Gr. ij to gr. v.

Syrupus Hypophosphitum

Syrup of Hypophosphites. Composed of hypophosphites of calcium, sodium and potassium.

Dose

Dose 1287

Sodii Pyrophosphas

Pyrophosphate of Sodium. In the form of colorless, translucent prisms, with a cooling saline taste and a feeble alkaline reaction, but no odor, soluble in water, but insoluble in alcohol. Dose. - Sodii Pyrophosphas 1288 to

Calcii Hypophosphis

(See Hypophosphite of Lime.) Sodii Hypophosphis. - Hypophosphite of Sodium. In the form of small, colorless or white prisms, or a white granular powder with a sweetish saline taste, and a neutral reaction, and soluble in water. Dose. - Gr. v to gr. x.

Therapeutic Uses

The phosphates are useful in rickets, mol-lities ossium, non-union of fractures, soft teeth of children, caries and necrosis of bone, anemia of nursing mothers, chronic bronchitis, leucorrhoea. The phosphate of soda in bilious sick headache, hepatic colic, jaundice, carbuncles, boils, etc., etc. The hypophosphites in phthisis, emphysema, fibroid lung, chronic tuberculosis, dilated bronchi, skin diseases, and all diseases characterized by mal-nutrition. Phosphoric and hypophosphoric acids are frequently combined with many vegetable and mineral tonics. The hypophosphites fulfill nearly all the indications of phosphorus itself.