In cases of this malady marked by op-pression and discomfort after eating, with a sense of weakness and emptiness at the stomach, thirst, offensive breath, coated and red-edged tongue, flatulence and pyrosis, with rejection of glairy acid fluid, and general symptoms of depression, coldness of extremities, and emaciation, I have had ample experience of the good effect of small doses. In acute gastric catarrh also, I have not been often disappointed, though a more cautious use is needed, but in the chronic forms, especially when coexisting with emphysema, with chronic bronchitis, or with phthisis, arsenic always gives some relief. Germain speaks favorably of the treatment (Gazette Hebdomadaire, 1860), and Trousseau remarks that the evidence in its favor is such as to warrant a fair trial of it. Many mineral waters that have a reputation in chronic gastric maladies contain an appreciable quantity of arsenic, notably those of Mont Dore, Plombieres, and Bus-sang. Dr. Wilson Fox, however, while referring to the favorable reports of others, states that "he has not had successful results himself, possibly because he has not seen definite indication for the remedy";. sometimes it seemed to aggravate the malady ("Reynolds' System," ii., p. 884).

Gastro-enteritis - "English Cholera." - Fowler's solution is an effective medicine in severe cases of this disorder. I have seen it give relief when the patient was suffering from retching and bilious or sanguineous vomiting, passing white, odorless, or slimy flocculent stools, with pain, tympanitis, and tenesmus; other symptoms present have been - thicklycoated tongue, thirst, pyrexia and prostration, muscular cramps, scanty urine, pinched and anxious features. Even when the stage of collapse has commenced, and the surface is dusky and covered with cold perspiration, the medicine has seemed to me of great service - 5 min. every one or two hours was the dose given, lessening it as the patient improved. Black has written very fully in praise of this remedy in English cholera, recommending 10 to 15 drops every ten to fifteen minutes till the sym-toms abate, then less frequently. He has found this most valuable in various forms of choleraic attack, but especially in serious cases connected with defective drainage, and presenting the symptoms of vomiting, purging, and rapid collapse; he records several instances of immediate and striking improvement (Lancet, ii., 1857). Dr. Hitchman speaks equally strongly, and describes fully the indications for arsenical treatment in such cases (loc. cit., p. 535).