Small doses (1/12 to 1/8 gr.) of the chloride exert a stimulant effect on the stomach-functions, increase the appetite, and often produce loose stools. Larger doses prove irritant or caustic; three grains, taken several times daily, soon induce a sense of pressure at the epigastrium, nausea, vomiting, and purging, with faintness (Fergusson: Dublin Journal, February, 1844). One drachm caused much vomiting and purging, and death from convulsion in seventeen hours (Walsh: Lancet, 1859). Half an ounce caused similar irritant symptoms, and death in two hours - evidence of severe gastro-intestinal inflammation was found (Taylor). The nitrate and acetate of baryta have also caused death, and the carbonate is commonly used as a poison for rats and mice. Although one teaspoonful is said to have destroyed life, much larger doses have been taken without fatal result.