Hufeland introduced this remedy for epilepsy in scrofulous subjects, but it is now seldom used. Brown-Sequard, however, while reporting against its efficacy, remarks that it may diminish reflex excitability, and therefore deserves trial in tetanus and in paralysis agitans. A somewhat doubtful case of traumatic tetanus is said to have recovered under the use of about 16 gr. of the chloride, given in twenty-four hours (Edinburgh Medical Journal, 1862). In satyriasis, or excessive sexual desire, it has also been employed. Dr. Hammond recommends it in diffuse and multiple cerebral sclerosis.

Preparations And Dose

Barii chloridum: the dose mentioned by Dr. Garrod and others is from 1/2 to 2 gr., but Mr. Kennedy, after much experience, maintains that 1/16 to 1/12 gr. is much more suitable and safer to commence with; very few persons, he says, can bear 1/8 gr. without irritation (Lancet, ii., 1873, p. 28). The United States Pharmacopoeia contains a liquor barii chloridi (1 part in 4 of distilled water); the dose ordered is 5 min.

As an eye-lotion, from 1 to 2 gr. may be ordered with 10 oz. of water. As a depilatory, 1 part of sulphide to 4 of excipient.

[Preparations, U. S. P. - Barii carbonas and Liquor barii chloridi.]