Currie, Giannini, and other early observers record benefit from cold applications in tetanus, and illustrations of it have been published by Dr. W. S. Playfair in his Indian experience (Medical Times, i., 1862). Of three severe cases of acute tetanus, two were markedly relieved by the application of ice in bladders along the spine; the third was considered too weak for a treatment which is in itself depressant, and this one only ended fatally.