The seeds of Strychnos Nuxvomica. East Indies.

Characters, - Nearly circular and flat, about an inch in diameter, urn-bilicated and slightly convex on one side, externally of an ash-grey colour, thickly covered with short satiny hairs, internally translucent, tough, and horny; taste intensely bitter, inodorous. The seeds to be pulverised must be heated by steam and dried.

Composition. - Two alkaloids, strychnine and brucine. The former is much less soluble in boiling water than the latter, and differs, further, in not being coloured by nitric acid, with which brucine gives a brilliant red. Both alkaloids are found combined with strychnic or igasuric acid - similar to malic acid.

Dose. - Of the powdered seed, 2-5 gr.

Preparations.

B.P.

Dose.

Extractum Nucis Vomicae.................................................................

1/4-2 gr.

Strychnina...........................................................................................

1/30-1/12 gr.

Tinctura Nucis Vomicae.....................................................................

10-20 min.

U.S.P.

Abstractum Nucis Vomicae...................................................................

1/2 gr.

Extractum ,, ,, ....................................................................

1/3-1 gr.

,, ,, ,, Fluidum......................................................

1-5 m.

Strychnina ............................................................................................

1/30-1/12 gr.

Tinctura Nucis Vomicae.......................................................................

10-20 mm.