This section is from the book "Materia Medica Pharmacy, Pharmacology And Therapeutics", by W. Hale White. Also available from Amazon: Materia Medica Pharmacy, Pharmacology And Therapeutics..
A neutral principle, in its commercial, more or less impure form, extracted from Goa or Araroba Powder, a substance found deposited in the wood of Andira Araroba Aguiar (nat. ord. Leguminosae).
A pale, orange-yellow, microcrystalline powder, odorless and tasteless; turning brownish-yellow on exposure to air.
The chief constituent of Goa powder is Chrysarobin, C27H30O14. Synonyms. - Rhein. Chrysophan (see p. 490). In the fresh plant it probably exists as a Glucoside, but this is slowly oxidized into Chryso-phanic Acid, C15H10O4, and glucose.
Chrysarobin, 5; Benzoinated Lard, 95.
It is a powerful irritant to the skin, which it stains yellowish brown. Linen is stained the same color. (The stain may be removed by a weak solution of caustic soda or chlorinated lime.) It is antiparasitic.
It is cathartic and very irritating to the stomach and bowels, causing vomiting and purging. It is excreted by the kidneys, and stains the urine yellow.
It is used as an antiparasitic in ringworm, and to excite healthy inflammation in chronic cutaneous diseases, especially psoriasis and acne rosacea. A pigment (chrysarobin, 1; solution of gutta percha, 9 solution of gutta percha is made by decantation of gutta percha, 1; lead carbonate, 1; chloroform, 9;) is more cleanly than the ointment and does not stain the clothes. Chrysarobin has also been given internally for skin diseases, but as it is so irritating this practice is not advisable.