This section is from the "A Practical Treatise On Materia Medica And Therapeutics" book, by Roberts Bartholow. Also available from Amazon: A Practical Treatise On Materia Medica And Therapeutics
Lactucarium. The concrete milk-juice of Lactuca virosa Linné (Nat. Ord. Compositae). (U. S. P.) Dose, gr. v— 3 j.
Dose, 3 ss— 3 ij.
Dose, 3 j— 3 iij.
Lactucarium contains several organic substances and eight to ten per cent of inorganic matter. It yields about fifty-eight per cent of lactucerine or lactucone, an inodorous, tasteless neutral substance, a crystallizable bitter principle, lactucine, and lac-tucic acid.
The soporific quality of lettuce is known to all who eat this vegetable. Notwithstanding this universal experience, careful experiments have shown that lactucarium possesses a very feeble hypnotic quality, if it be not entirely inert. It is only used as a substitute for opium and its alkaloids when these disagree. The sirup of lactucarium is prescribed to relieve cough, but it is better employed as a vehicle for more powerful agents of the class of expectorants.
 
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