A. Persistent pruritus. De Haen. **

Grayish discolorations, Cazenave (Jour. hebd. '28), 39, 80. Brownish discolorations, v. Veiel (170, '60), 39, 83; Mayer (Ann. ae la Soc. de med. d'Anvers, '44), 39, 84; 47, 195; Charcot, 117, June 30, '64; 41, 137. Rubeoloid eruption, Thomson (Med. Essays and Obs. 1747), 39, 31;

Macnab, 148, 1/08, 297; Fox, 146, 1/68,327; Begbie, 126, Ma '58; 41, 137. Erythema, Kellie, 127, April, '08; Hooper, 187, '47,508; Champouillon, 178, '50; Marchand (Ann. med. de la Flandre, '51 and '54), 39, 19; Vaudey (These de Strasbourg, '70), 39, 20; Fox, 137, 1/67, 209. Urticaria, Fowler; | Kersten (120, '51), 39, 27. Miliary eruption, Hahnbaum (Henke's Zeitsc. '21), 39, 41. Vesicular eruption, 209.

* Annales de Chimie, 7?: 187.

+ Reportorium fur die Pharmacie. 3: Nurnberg, 1817

++ Deutschlands wildwachsende Arzney-Pflansen. Stuttgart, 1888. ** Ratio medendi. Pars, ix. Vienna, 1764, p. 252. | Medical reports of the effects of Arsenic. Loudon, 1786, p. 97.

Furuncles, Vaudey (loc. eft.), 39, 76; 47, 195; Girdlestone, 141, '06, 297; 203.

Petechiae, M'Leod, 127, Oct. '19, 554; 54, 1: 396.

Lichenoid eruption, Fox, 137, 1/07, 455.

An eruption which gradually put on the character of eczema, Christison, 126, Jan. '50, 630.

Papulo-erythematous eruption, dry and livid on wrists and neck,general papular eruption on trunk and extremities, with pruritus, Eruption of clusters of vesicles on an inflamed base, extending from lower part of the arm, down the back of forearm and hand, including back of the fingers, Finlayson, 162, July, '78.

Herpes labialis and preputialis, Hutchinson, 146, 1/69, 408.

Zoster, 4, 105; Sisson, 162,'69, 70; Duffin, 137, 2/69, 508; Finlayson, loc. cit.; Hutchinson, 146, 2/68, 722; Fox, 137, 1/07, 455.

Defluvium capillorum et unguium, 4, 105; 7, 195; 1, 1243; Girdle-stone, loc. cit.

Dryness of the skin, heat and itchiness of the eyelids, minute papular rash followed by fine desquamation, Begbie, 126, May, '58, (H.G.P.)

Soles of the feet and palms of the hands become a little hard and corny. The epithelial scales are thickened, desquamation and papules, Hunt, 135, 2: 147.

Delicate desquamation of the epidermis, delicate papular eruption, 70, 21.

General desquamation except of the head, De Haen, op. cit.

The skin becomes dry and dirty-looking, and a slight branniness may be noticed, most marked where the skin is covered with clothes. Eczema or urticaria may arise, or perhaps vesication or mere desquamation, with tenderness of the hands or soles of the feet. The hair, and even the nails, sometimes fall off. In arsenical poisoning a petechial papulo-vesicular and wheal-like rash often appears from the second to the fifth day, 5, 224-5.

Itching of the eyelids, urticaria, eczema, pityriasis, and psoriasis, 4, 105.

Diaphoresis, pruritus, eczema, pustules, desquamation, and pigment spots, 38, 64-9.

Eruption of pustules on the face, shoulders, arms, and chest, 37, 1: 4.

Alopecia areata, Wyss, 108, '70, 395.

Eliminated in the sweat, Bergeron et Lemattre (Arch. gen. de med., '64),38,64.

In its elimination by the skin it unquestionably influences the functions of that organ; it is this action that is utilized in the treatment of cutaneous diseases, 38, 69.

(In dogs.) Circumscribed erythematous eruptions near the joints, fallingof the hair, leaving red, dry surfaces, vesicles on the abdomen, 38, 68.

B. According to Dr. Braemer, in Cassel, there exists among those who have much to do with arsenic, an arsenical eruption which consists of small vesicles like those of scabies; the eruption prefers the scrotum and thigh, 1, 1247.

Some workmen used arsenic by mistake for polishing purposes. In six of them minute papules appeared on face and scrotum, with redness and itching of the parts, and minute pustules on lingers, and around the nails, Ogston, 133, '51, 184.

Nose, mouth, cheeks, and forehead were the seat of numerous small vesicles. On back of hands similar eruption, mingled with vesico-pustules with slight indurated base. Skin tuinefied (from finely powdered arsenic coming in contact with the face), Behier, 178, May 27, '75. Erysipelas, Belloc (Cours de med. leg., an IX.), 39, 21.

(From a lotion.) Severe pruritus and small pustules, Barrier (Jour. de med., 1783), 39, 39.

(From lotion to scalp.) On the eighth day the entire body cow: with minute pustules, especially on hands and feet, Desgranges (Receuil periodique, 1799), 39, 40.

(Lotion to scalp.) On second day, body greatly swollen, and cov-ered with livid vesicles, followed by death, Portalez (Jour. de med. de Corvisart, '03), 39, 40.

(Lotion to scalp.) Erysipelas of head and face, shoulders, neck, and chest, Reiner (Lehrb. d. chem. '12), 39, 23.

Ulcers, which are deep, and coated on the surface by a buff-colored gelatinous-looking lymph, bordered by a dark red margin and surrounded by a purplish-red, thickened, and desquamating areola, 78, 151.

C. Psoriasis, Girdlestone, 141, '06, 297, and many others. Eczema, T. Y., 141, '07, 255, and many others.

Pemphigus, Ramskill (187, Jan. 4. '62), 17, 741; 71, 134; Hutchinson, 146, 2/75, 23; 4, 113, (H.G.P.)

Urticaria, 99, 108; 210.

Furuncles, 4, 113; Schweich (B. & F. M. R. '48), 44, 112; 210.

Warts, 56, 56; 202.

Lupus, 70, 16 75, 123; 95, 218 et seq.

Epithelioma, rodent ulcer, 4, 113.

Epithelioma, lupus, 207.

Syphilitic nodes and pains, Colhoun, 105, 3: 347; Eberle, 105, 4: 460.

Syphilis (late lesions), 205.

Obstinate syphilides, leprosy, and scaly eruptions, 1, 1245.

Molluscum contagiosum, 57, 258.

Lichen ruber, 97, 1: 397; 1, 1250.

D. Lupus, 75, 123; 95, 218 et seq. (Fowler's Sol.); Lang, 177, No. 48,

Cancerous growths, Justamond;* 54,1: 409; D'Onnea, 131, 2: 418, and many others.

Leprosy (in ointment, gr. x. to i.); Colles, 137, 1/64, 408.