The cutis under the bullae presented three distinct areas of morbid change. The innermost area was composed of a structureless, almost homogeneous, but faintly granular substance, containing at several points rows of leucocytes; the middle area was composed of a layer of exudation cells suspended in a very delicate reticulum; the outer was formed by remnants of connective-tissue bundles separated from each other by wide spaces. There were a few blood-vessels in the second area, and a large number in the third. The vessels were distended by red corpuscles, and their walls were in many instances partially disorganized. The substance in the inner area consisted of coagulated albuminous material from the blood. The third area was bounded almost abruptly by the ordinary bundles of connective tissue of the cutis. The sebaceous glands were unaffected. Portions of blood-vessels in the deeper strata of the cutis, and distant from the bulla and from the sebaceous glands, were found distended and plugged with disorganized blood. The epidermis over the inner area was ruptured and disorganized. The bulla was formed by injury to the walls of the blood-vessels of a limited area, and by consequent escape of blood, which displaced the connective tissue, pierced the rete mu-cosum, and accumulated under the horny layer of the epidermis, Thin., 137, 2/78, 696.