I have seen very decided benefit follow the use of this drug, but am not prepared to give it the high commendation accorded it.

* By poisonous dotes we here mean such doses as will cause marked constitutional disturbance, and perhaps endanger the future welfare of the patient. As examples I will state that I bare twice seen Psoriasis disappear as if by magic after a few tea-spoonful doses of Fowler's solution which the patients bad taken through misunderstanding. I have also known serious consequences follow too large doses of phosphorus by many of the older writers, more especially Crichton (p. 51). Possibly I have not yet learned how to use it to the best advantage.

+ I have at present, a case of psoriasis and one of eczema, in which very moderate doses of arsenic will in a short time produce anasarca with albuminuria.

Phosphorus - This drug, in doses of from gr. 1/100 to gr.1/25, exerts very distinct influence on Psoriasis. The dangers connected with its use, however, are not to be overlooked. These are the induction of pleuritis and of acute fatty degeneration of the liver. The former I have met with, the latter it has not been my ill-fortune to encounter.

Of the external applications that are of service in Psoriasis, the various tars, carbolic acid, and Vlemingkx's solution, together with the various sorts of baths, have been fully considered in the quotation from Hebra. There is little doubt that they will accomplish all that is there claimed for them. One drug, however, of recent introduction, requires special mention: